二甲双胍治疗2型糖尿病合并非酒精性脂肪肝病疗效及不良反应分析

The Efficacy and Side Effects of Metformin in the Treatment of Type 2 Diabetes Mellitus Complicated With Non-alcoholic Fatty Liver Disease

目的探讨二甲双胍治疗2型糖尿病合并非酒精性脂肪肝患者的疗效及不良反应。方法选择90例2型糖尿病合并非酒精性脂肪肝患者,随机分为两组,各45例。对照组在健康教育的同时采用生活干预,实验组在生活干预的同时采用二甲双胍,观察两组患者疗效及不良反应。结果实验组治疗有效率高于对照组,实验组患者治疗后的各项指标优于对照组;两组均未发生明显的不良反应。结论常规疗法结合二甲双胍,可显著改善治疗效果,具有较好的安全性。

Objective To investigate the effect of metformin in treatment of type 2 diabetes with efficacy and adverse reactions in patients with nonalcoholic fattyliver disease. Methods 90 cases of nonalcoholic fatty liver disease in patients with type 2 diabetes were randomly divided into two groups,45 cases in each group. The health education and the intervention of life were used in control group,at the same time the experimental group with metformin in life intervention,the curative effect and adverse reaction of two groups. Results The effective rate of the treatment group was significantly higher than the control group,each index was better than the patients in the the control group after the treatment; there were no obvious adverse reactions the two groups. Conclusion Routine therapy combined with metformin can significantly improve the treatment effect,has Better security.