对比异甘草酸镁与复方甘草酸苷治疗慢性肝炎的临床效果

The Clinical Effect of Magnesium Isoglycyrrhizinate or Compound Glycyrrhizin in the Treatment of Chronic Hepatitis

目的研究分析慢性肝炎患者接受异甘草酸镁和复方甘草酸苷治疗的效果。方法根据2014年9月~2015年12月我院的103例慢性肝炎患者进行研究分析,将患者分为对照组和研究组,对照组51例使用复方甘草酸苷治疗,研究组52例使用异甘草酸镁治疗,对两组患者的治疗情况进行比较分析。结果研究组的临床治疗有效率是94.2%,5.8%无效,对照组有效率是74.5%,25.5%无效,两组的有效率对比差异有统计学意义（P〈0.05）;对照组有2例不良反应,经治疗均好转,研究组无不良反应病例。结论慢性肝炎患者接受异甘草酸镁及复方甘草酸苷治疗的效果均较好,而且异甘草酸镁效果优于复方甘草酸苷。

Objective To study the effect of the treatment of chronic hepatitis patients with magnesium isoglycyrrhizinate and compound glycyrrhizin. Methods 103 cases of chronic hepatitis B patients in our hospital were chose to carry on the research analysis from September 2014 to December 2015. Patients were divided into control group and study group,51 cases in the control group used compound glycyrrhizin,52 patients in study group used magnesium isoglycyrrhizinate. The treatment effect of the two groups were compared. Results The effective rate of the study group was 94.2%,5.8% invalid,the effective rate of the control group was 74.5%,25.5% invalid. There was significant difference between the two groups（P〈0.05）. The control group had 2 cases of adverse reactions,all cases were relieved after treatment,the study group had no adverse reaction cases. Conclusion The chronic hepatitis patients with magnesium isoglycyrrhizinate and compound glycyrrhizin is effective,and the effect of magnesium isoglycyrrhizinate is better than that of compound glycyrrhizin.