阿莫西林与阿莫西林—克拉维酸钾不良反应的对比研究

A Comparative Study on Adverse Reactions of Amoxicillin and Amoxicillin and Clavulanate Potassium

目的探讨阿莫西林和阿莫西林-克拉维酸钾的不良反应情况。方法选取我院的180例感染性疾病患者来分析研究,共分成对照组和观察组,均有90例,对照组患者接受阿莫西林治疗,观察组接受阿莫西林-克拉维酸钾治疗,比较两组患者的不良反应情况。结果观察组患者的不良反应发生率优于对照组,差异有统计学意义(P<0.05)。两组的治疗效果对比,观察组优秀,差异有统计学意义(P<0.05)。结论感染性疾病患者接受阿莫西林-克拉维酸钾治疗的安全性比阿莫西林高,应用价值高。

Objective To investigate the adverse reactions of amoxicillin and amoxicillin and clavulanate potassium. Methods In our hospital,180 cases of patients with infectious diseases were divided into control group and observation group,90 cases in each group. Patients in the control group received amoxicillin for treatment,the observation group received amoxicillin and clavulanic potassium,compared two groups of patients with adverse reactions. Results The incidence of adverse reactions in the observation group was better than that in the control group,the difference was significant（P〈0.05）. The therapeutic effect of the two groups was compared,the observation group was better,and the results were statistically significant（P〈0.05）. Conclusion It is safe to use amoxicillin and clavulanate potassium for patients with infectious diseases,and the application value is high.