地佐辛联合舒芬太尼在肛肠手术术后镇痛的临床研究

Clinical Study of Dizocine Combined With Sufentanil on Postoperative Analgesia in Anorectal Surgery

目的探讨采用地佐辛联合舒芬太尼对肛肠手术后疼痛的治疗效果及临床价值。方法随机选择肛肠手术治疗的患者300例,根据随机分组原则,将其分为实验组与对照组,每组各150例。实验组术后采用地佐辛复合舒芬太尼镇痛,对照组采用舒芬太尼,比较两组患者术后镇静效果。结果两组患者术后各时间点静息状态、翻身运动VAS评分、镇静Ramsay评分比较,差异无统计学意义(P>0.05);实验组不良反应发生率低于对照组(P<0.05)。结论地佐辛复合舒芬太尼术后镇痛效果与舒芬太尼相似,有利于患者及早康复。

Objective To explore the effect and clinical value of combined use of dizocin and sufentanil in the treatment of pain after anorectal surgery. Methods 300 cases of patients of anorectal surgery were randomized and were divided into experimental group and control group,150 cases of patients in each group. Experimental group was treated with the combination with dizocin and sufentanil,control group was treated with sufentanil,to compare two groups after sedation. Results There were no statistically significant differences in resting state,VAS bisection and sedative Ramsay scores between the two groups at each time point after operation（P〉0.05）. The incidence of adverse reactions in the experimental group was significantly lower than that in the control group（P〈0.05）. Conclusion The analgesic effect of dizocin combined with sufentanil is similar to that of sufentanil,which is beneficial to early rehabilitation.