孕妇及受血者输血前用免疫微柱凝胶法进行不规则抗体筛查的结果分析

Analysis of Results of Immuno-microcolumn Screening for Irregular Antibody Screening in Pregnant Women and Recipients Before Transfusion

目的总结孕妇及受血者输血前用免疫微柱凝胶法进行不规则抗体筛查的结果,最大程度上保证临床输血安全,保证母婴安全。方法选取我院在2013年1月~2016年1月来自住院部、门诊、急诊产科提供的2 007份不规则抗体筛查、结果作为研究对象,并借助免疫微柱凝胶法、试管法间接抗人球蛋白法进行不规则抗体检测。结果 7例阳性标本之中,经抗体特异性鉴定,抗D阳性1例,抗E阳性2例,抗e阳性1例,抗C阳性1例,抗Lewis、抗Diego阳性各1例。结论患者在输血前,对其进行不规则抗体筛查、检定工作,能够保证输血的安全性,可以避免免疫性溶血问题,预防新生儿溶血病发生。

Objective To summarize the results of immuno-microcolumn screening for irregular antibody screening before transfusion in pregnant women and recipients, and to ensure the safety of clinical blood transfusion to ensure the safety of mother and infant. Methods The subjects of our study were 2 007 cases of irregular antibody screening from inpatient department, outpatient department and emergency obstetrics department in our hospital from January 2013 to January 2016. The results were analyzed by immuno-micro column gel method, Method of indirect anti-human globulin method for detection of irregular antibodies. Results 7 cases of positive samples. The antibody specificity identification, D positive resistance in 1 case, E positive resistance in 2 cases, e positive resistance in 1 case, C positive resistance in 1 case, Lewis resistance, resistance to Diego positive in 1 case. Conclusion Before the blood transfusion, the screening and checking of irregular antibodies can ensure the safety of blood transfusion, and avoid the problem of hemolysis and prevent the hemolytic disease of newborn.