剖宫产术围手术期用药的临床对策

Clinical countermeasures in perioperative medication of cesarean section

目的探讨剖宫产术围手术期用药的临床对策。方法 80例行剖宫产术产妇,随机分成观察组和对照组,各40例。观察组产妇采用围手术期抗感染用药治疗,对照组产妇采用围手术期常规用药治疗,对比不同用药后的治疗效果。结果观察组产妇术后退热时间为(1.45±1.07)d,术后最高体温为(37.80±0.20)℃,术后腹部切口感染率为2.5%(1/40),产褥病发生率为2.5%(1/40);对照组产妇术后退热时间为(2.68±1.8)d,术后最高体温为(38.31±0.28)℃,术后腹部切口感染率为15.0%(6/40),产褥病发生率为17.5%(7/40);两组产妇术后退热时间、最高体温及腹部切口感染率、产褥病发生率比较,差异均有统计学意义(P<0.05)。结论剖宫产术产妇在围手术期给予抗感染用药治疗可明显缩短预防性使用抗菌药的使用时间,降低切口感染率及产褥病发生率。

Objective To investigate clinical countermeasures in perioperative medication of cesarean section. Methods A total of 80 puerpera receiving cesarean section were randomly divided into observation group and control group, with 40 cases in each group. The observation group received perioperative anti-inflammation medication treatment, and the control group received perioperative conventional medication treatment. Curative effects after different treatment were compared. Results The observation group had postoperative fever clearance time as（1.45±1.07）d, postoperative maximal body temperature as（37.80±0.20）℃, postoperative infection rate of abdominal incision as 2.5%（1/40）, and incidence of puerperalism as 2.5%（1/40）. The control group had postoperative fever clearance time as（2.68±1.8）d, postoperative maximal body temperature as（38.31±0.28）℃, postoperative infection rate of abdominal incision as 15.0%（6/40）, and incidence of puerperalism as 17.5%（7/40）. The differences of postoperative fever clearance time, maximal body temperature, infection rate of abdominal incision and incidence of puerperalism all had statistical significance between the two groups（P〈0.05）. Conclusion Implement of perioperative anti-inflammation medication treatment for puerpera receiving cesarean section can remarkably shorten administration time of preventive antibacterial and reduce infection rate of incision and puerperalism.