依达拉奉与丹参注射液联合方案治疗急性脑梗塞的临床效果分析

The Clinical Curative Effect of Edaravone Combined with Salvia Miltiorrhiza Injection in Treatment of Acute Cerebral Infarction

目的探讨依达拉奉与丹参注射液联合方案治疗急性脑梗塞的临床疗效,为临床合理用药提供参考。方法选择2014年9月~2016年3月收治的急性脑梗塞患者88例作为研究对象,随机将88例患者分成对照组与治疗组,两组分别有患者44例,对照组单纯应用丹参注射液治疗,治疗组应用依达拉奉与丹参注射液联合方案治疗,比较两组患者的临床效果。结果治疗组患者治疗后BV、PV、Fib、PCV水平以及NIHSS评分均要显著低于对照组与治疗前（P〈0.05）;治疗组临床总有效率是90.91%,对照组临床总有效率是72.73%,治疗组临床疗效要显著优于对照组（P〈0.05）。结论急性脑梗塞患者应用依达拉奉与丹参注射液联合方案治疗具有显著临床效果,能够加快神经功能恢复,改善患者体内血液流变学状态,值得在临床上大力推广应用。

Objective To investigate the clinical curative effect of edaravone combined with Salvia miltiorrhiza injection in treatment of acute cerebral infarction,and to provide reference for clinical rational drug use.Methods A total of 88 cases with acute cerebral infarction in Liaoyang Hospital of TCM from September 2014 to March 2016 were selected as the research subjects.These patients were randomly divided into the control group and the treatment group,44 cases with each group.the control group was only treated with Salvia miltiorrhiza injection,and the treatment group received edaravone combined with Salvia miltiorrhiza injection treatment regimen,the clinical effects of the two groups were compared.Results After treatment,the levels of BV,PV,Fib,PCV and NIHSS score in the treatment group were significantly lower than those in the control group and before treatment（P〈0.05）; the clinical total effective rate of the treatment group and the control group were 90.91% and 72.73%,respectively,and the clinical curative effect of the treatment group was significantly higher than that of the control group（P〈0.05）.Conclusions The clinical curative effect of edaravone combined with Salvia miltiorrhiza injection in treatment of acute cerebral infarction is remarkable.The treatment regimen can accelerate the recovery of neurological function,improve the patient＇s blood rheology state,it is worth in clinical application.