摘要
目的观察布托啡诺、吗啡用于高龄患者术后硬膜外自控镇痛的安全性比较。方法60例高龄下肢手术患者行连续硬膜外麻醉随机分为两组:B组和M组。分别于术后2 h(T1)、6 h(T2)、12 h(T3)、24 h(T4)、48 h(T5)监测并记录患者潮气量(VT)、肺活量(VC)、呼吸频率(RR);抽取动脉血监测PH、Pa CO2、Pa O2、Sa O2等指标。结果 M组在T2、T3时RR、VC、Pa O2明显低于B组,且与同组T0时相比也明显降低有显著性差异(P<0.05);而Pa CO2在T2、T3时明显高于B组,且与同组T0时相比也明显升高,均有显著性差异(P<0.05)。结论布托啡诺应用于高龄患者硬膜外自控镇痛时,对呼吸系统抑制较轻,安全性好。
Objective To observe Bhutto butorphanol,morphine for elderly patients with postoperative epidural analgesia safety.Methods 60 cases of elderly patients with lower extremity surgery were randomly divided into two groups:group B and group M.Respectively after operation(T1) 2 h,6 h(T2),12 h(T3),24 h(T4),and H(T5) monitoring and recording with moisture amount(VT),vital capacity(VC),respiratory rate(RR); draw the arterial monitoring of blood p H,Pa CO2,Pa O2 and Sa O2 of indicators.Results in group M at T2 and T3 RR,VC,Pa O2 was significantly lower than that in group B and also significantly decreased significantly(P〈0.05) compared with the same group of t0; and Pa CO2 in T2,T3 was significantly higher than that of group B and was significantly increased,compared with the same group of t0.There were significant differences(P〈0.05).Conclusions Bhutto butorphanol applied in elderly patients controlled epidural analgesia on respiratory inhibition,lighter,good safety.
作者
肖建波
滑炜
XIAO Jianbo HUA Wei(Department of Anesthesiology, Xi'an Hospital of AVIC, Xi'an , Shaanxi,710077)
出处
《航空航天医学杂志》
2016年第12期1514-1517,共4页
Journal of Aerospace medicine
关键词
布托啡诺
吗啡
硬膜外自控镇痛
安全性
butorphanol
morphine
Patient-controlled epidural analgesia
safety