IL-1及家族成员在心肌炎中的作用研究

Study the Role of IL-1 and Its Family Members in Myocarditis

心肌炎是多种因素引起心肌局限性或弥漫性的炎症病变,近年来许多专家学者对该病进行了大量的研究,但是它的发病机制一直尚未明确。随着心肌炎动物模型试验的基础研究与临床诊疗的不断深入,目前认为心肌炎的发病主要与病毒损伤心肌细胞、免疫机制有关,在此过程中细胞因子IL-1及其家族成员起着重要的作用,本文就IL-1及家族成员在心肌炎的作用机制的研究进展综述如下。

Myocarditis is a variety of factors cause myocardial limitations or diffuse inflammation pathological changes, many experts and scholars have made a lot of research on this disease in recent years, but its pathogenesis has not been clear. With the continuous study of animal model of myocarditis and the continuous deepening of the clinical data of patients, the pathogenesis of myocarditis is mainly related to the viral damage of cardiac muscle cells and immune mechanism at present, IL- 1 and its family members play an important role in this process, This article reviews the role of IL-1 and its family members in myocarditis.