级联激活的免疫细胞对晚期非小细胞肺癌患者免疫功能及生活质量的影响

Effects of Cascade Primed Immune Cells on Immunity Function and Quality of Life of Patients with Advanced Non-small Cell Lung Cancer

为了探讨级联激活的免疫细胞(CAPRI)对晚期非小细胞肺癌患者免疫功能及生活质量的影响,将47例晚期非小细胞肺癌患者随机分为治疗组(24例)和对照组(23例),分别给予化疗+CAPRI治疗和化疗。结果示治疗组患者的免疫功能及生活质量和对照组比较明显改善(P<0.05),治疗组和对照组不良反应发生率比较差异无统计学意义(P>0.05)。因此,CAPRI治疗可以改善晚期非小细胞肺癌化疗患者的免疫功能和生活质量,且安全有效。

To investigate the effects of cascade primed immune cells（CAPRI）on the immune function and quality of life of patients,47 patients with advanced non-small cell lung cancer（NSCLC）were randomly divided into treatment group（24patients）and control group（23 patients）,then they received chemotherapy ＋ CAPRI therapy and chemotherapy respectively.The results show that the immune function and quality of life of treatment group were significant improved comparing with control group（P0.05）.There was no significant statistically difference of the side effects between two groups（P0.05）.Therefore,CAPRI cell therapy is safe and effective,it can improve immune function and quality of life of patients with advanced non-small cell lung cancer.