浙江省金华市人群麻疹、腮腺炎、水痘、乙型病毒性肝炎和甲型病毒性肝炎抗体水平监测分析

Surveillance for antibody levels against varicella,hepatitis B and hepatitis A in healthy population in Jinhua,Zhejiang

目的了解浙江省金华市健康人群麻疹、腮腺炎、水痘、乙型病毒性肝炎(乙肝)和甲型病毒性肝炎(甲肝)的抗体水平情况,为制订和完善免疫策略提供科学依据。方法采用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)检测麻疹IgG、腮腺炎IgG、水痘IgG、乙肝表面抗体(HBs Ab)和甲肝IgG。结果共检测1170份血清标本,麻疹、腮腺炎、水痘IgG阳性率分别为89.40%、80.34%和71.37%,HBs Ab阳性率为78.29%,甲肝IgG阳性率为55.21%。结论金华市健康人群麻疹、腮腺炎具有较高的免疫水平,乙肝、水痘和甲肝免疫水平较低,应重点关注水痘、甲肝疫情,同时进一步做好免疫预防接种工作,提高人群免疫覆盖水平。

Objective To understand the antibody levels against measles,mumps,varicella,hepatitis B and hepatitis A in healthy population in Jinhua,Zhejiang province,and provide scientific evidence for the development and improvement of immunization strategy.Methods Enzyme-linked immunosorbent assay（ELISA） was conducted to detect measles IgG,mumps IgG,varicella IgG,HBs Ab and hepatitis A IgG.Results A total of 1170 serum samples were tested.The positive rates of measles IgG,mumps IgG,varicella IgG,HBs Ab and hepatitis A IgG were 89.40%,80.34%,71.37%,78.29%and 55.21%,respectively.Conclusion The antibody levels against measles and mumps were high,but the antibody levels against varicella,hepatitis B and hepatitis A were lowin healthy population in Jinhua.Close attention should be paid to the possible outbreaks of chickenpox and hepatitis A,and the vaccination should be strengthened to expand the coverage in healthy population.