快速气相色谱/电子轰击离子源-飞行时间质谱联用仪的研制

Development of Fast Gas Chromatography/Electron Impact Ion Source of Time-of-Flight Mass Spectrometry

基于快速气相色谱分析技术和飞行时间质谱技术,研制了快速气相色谱/电子轰击离子源-飞行时间质谱联用仪。仪器由进样系统、气相色谱分离系统、气质接口、电子轰击离子源、垂直引入反射式飞行时间质量分析器、数据采集系统和硬件控制系统等组成。设计了汽化室、加热膜色谱柱和一种三层套管的传输管用于连接色谱与质谱。以烃类混合标准气体为对象,对载气压力、色谱柱温度和电压参数进行了优化,实现了对各类有机物的快速分离和准确定性。最后,将该方法用于测试苯系物和异丁烷标气,进行了仪器性能测试。结果表明,质量范围是4~502 amu,分辨率优于500,检测限为500 ppb,分析时间小于5 min,重现性RSD小于10%,动态范围达到四个数量级。

Based on fast gas chromatograph and time-of-flight mass spectrum technology, fast gas chromatog- raphy/electron impaction source of time-of-flight mass spectrometer （FGC/EI-TOF MS） is developed. The FGC/EI-TOF MS is mainly composed of a sample system, a GC separation system, a GC-MS interface, an electron impaction source, a vertical introduction of reflection time-of-flight mass analyzer, a data acquisition system and hardware control system. A vaporization chamber, heating film of GC and three-wall-tube line are built. After the optimization of EPC, temperature of GC, and important voltage parameters, Alkanes standard gas mixtures are studied, and fast seperation and accurate classification different kinds of organic compounds are eventually realized rapidly and accurately. At last, the FGC-TOF MS is applied to test the characteristics of benzenes and isobutane standard gas mixtures. The results indicate that mass range is 4~502 amu, resolution is better than 500, detection limit is 500 ppb, analysis time is less than 5 min, reproducibility RSD is less than 10%, dynamic range is four orders of magnitude.