双源CT双能量成像诊断痛风结节沉积的价值分析

Analysis of dual energy CT imaging in the diagnosis of gouty tophus deposition value

目的评估双源CT双能量成像在诊断痛风结节沉积的临床价值。方法选取该院2012年12月至2015年12月收治的痛风患者65例,另选同期收治的65例非痛风患者(类风湿性关节炎、退行性骨性关节炎及不明原因下肢疼痛)作为对照组,双源CT双能量扫描两组患者的疼痛部位,比较两组患者的尿酸盐沉积差异。挑选3名有经验的临床医生,在不了解影像学结果的情况下通过问病史和体格检查对痛风组患者尿酸盐沉积状况(痛风结节)进行评估,比较临床评估与双源CT双能量成像结果的差异。结果双源CT双能量成像显示对照组无痛风结节沉积,痛风组患者在腕关节、膝关节及足踝关节检测出痛风结节沉积的比例分别为96.06%(33/34),100.00%(22/22)和96.49%(55/57)。65例患者经双源CT双能量成像共检测出痛风结节沉积部位545处,是医生临床评估(125处)认定的4.36倍。结论双源CT双能量成像诊断痛风结节沉积无创简便,准确率高,漏诊率低,应作为临床筛查痛风病的重要检查方法。

Objective To explore the value of dual energy CT imaging in the diagnosis of gouty tophus deposition. Methods Sixty-five cases of patients with gout treated in this hospital between December 2012 to December 2015 were selected. Another （;5 cases of patients（rheumatoid arthritis,degenerative osteoarthritis and unexplained leg pain） were selected as control group. The re- sults of dual energy CT imaging between two group were compared. Three experienced clinicians who didn＇t understand the imaging results were selected. They had a medical history and physical examination in patients with gout, The differences between clinical e- valuation and imaging results were compared. Results Dual energy CT imaging showed that there were no tophi deposition in con- trol group^the topi deposition in wrist joint,knee joint and ankle joint were 6.06%（33/34） ,100.00~/~ （22/22） and 96.49 ~/~0 （55/57） in gout group. Dual energy CT imaging detected a total of 545 parts of tophus deposition. It was 4.36 times of the result of clinical evaluation（125 parts）. Conclusion Dual energy CT imaging shows the advantages of simple noninvasive,high accuracy and low rate of misdiagnosis in diagnosing gout nodules.