益诺胶囊用于负压吸宫术及分娩后的疗效观察

Observation of clinical effectiveness of Yinuo capsule used in women after uterine aspiration or postpartum

目的:探讨益诺胶囊用于人工流产负压吸宫术、剖宫产及阴道分娩后的临床疗效。方法:将186例行负压吸宫术流产妇女随机分为观察组和对照组,观察组术后即开始口服益诺胶囊0.64g,Bid,疗程6d,对照组未服用该药,随访至流产后第一次月经来潮。观察并比较两组的阴道出血量、出血持续时间、月经恢复时间及盆腔感染发生率。将248例剖宫产者、202例阴道分娩者分别随机分为观察组和对照组,两观察组均在产后第1天开始口服益诺胶囊0.64g,Bid,疗程8d,并联合缩宫素应用,对照组在产后仅给予缩宫素,随访至产后42d。观察并比较剖宫产及阴道分娩各自观察组与对照组在分娩后恶露持续时间、产褥感染的发生率、产后5d子宫底下降平均速度及产后10d宫腔积液的情况。结果:负压吸宫术观察组术后阴道出血量、出血持续时间及盆腔感染的发生率小于对照组(P<0.05),与对照组月经恢复时间比较无差异(P>0.05)。剖宫产及阴道分娩观察组产后恶露持续时间、宫腔积液及产褥感染的发生率均小于对照组,产后5d宫底下降速度大于对照组(均P<0.05)。结论:人工流产负压吸宫术、剖宫产及阴道分娩后口服益诺胶囊,有促进子宫复旧和防治感染的作用,值得在临床上探索应用。

Objective： To observe the clinical effect of Yinuo capsule used for women after uterine aspiration, cesarean section or vaginal delivery. Methods： Totally 186 women undergoing uterine aspiration were randomly divided into ob- servation group and control group. The women in observation group received 6--day treatment by oral Yinuo capsules after abortion immediately, while the women in control group were not given Yinuo capsules. All the women were fol- lowed up to the first time of menstrual recovered. The bleeding volume, bleeding duration, menstruation recovery time and incidence of pelvic infection of women were observed and compared between the two groups. In addition, another totally 248 women with cesarean section and 202 women with vaginal delivery were also randomly divided into observa- tion group and control group, respectively. The postpartum women in both observation groups received 8--day treat- ment by Yinuo capsules and oxytocin, while postpartum women in both control groups were only given oxytocin, and all of women were followed-- up for postpartum 42 days. Time of lochia, incidence of puerperal infection, average speed decreased of uterine fundus during 5 days, and incidence of uterine cavity effusion after 10 days of women were observed and compared between the two groups. Results： As for women undergoing uterine aspiration, the amount of vaginal bleeding, the time of bleeding, and incidence of pelvic infection of women in the observation group were signifi- cant less than those of women in the control group （P〈0.05）, but there was no significant difference on the time of menstruation recovery between the two groups （P〉0.05）. As for women undergone cesarean section or vaginal deliv- ery, the time of lochia continual, the incidence of puerperal infection, and the incidence of uterine cavity effusion of women at postpartum 10 days in observed groups were less than those of women in control groups （P〈0.05）, and the average decreased speed of uterine fundus of women during postpartum 5 days in observation groups were faster than those of women in control groups （P〈0.05）. Conclusion： Women using Yinuo capsule after uterine aspiration,cesarean section or vaginal delivery can promote recovery of uterus and decrease inflammatory , so Yinuo capsule is worthy to promoting application.