河北省邱县2011-2014年4238例手足口病病例临床分析

Analysis of hand-foot-mouth cases in central hospital of Qiuxian of Hebei Province from 2011 to 2014

目的调查河北省邱县手足口病流行现状。方法采集邱县2011-2014年手足口病病例的肛拭子或咽拭子标本,对其进行病原学检测。结果 2011-2014年邱县手足口病病例逐年增加,Cox Al6和EV 71感染率差异有统计学意义(χ~2=7.022,P=0.021)。2~3岁组儿童是手足口病的高发人群;手足口病感染季节性强,4~7月为发病高峰。结论邱县手足口病疫情与病例年龄、时间密切相关,加强环境卫生管理是预防手足口病的主要措施。

Objective To investigate the epidemiological characteristics of hand,foot mouth disease（ HFMD） reported in Qiuxian from 2011 to 2014. Methods From 2011 to 2014,samples were collected from HFMD patients and the pathogens were analyzed. Results The study results indicated that the prevalence of HFMD showed an increasing tendency in Qiuxian from 2011 to 2014,and the infection rate between Cox Al6 and EV 71 showed the significant difference（ χ^2= 7. 022,P = 0. 021）. The children with 2 to 3 years were infected with HFMD. Furthermore,HFMD was associated with the changing of seasonsand easily occurred from April to July. Conclusion HFMD is related to children patients＇ age,and fluctuates with the changing of seasons. We should improve the environmental health,to reduce the HFMD epidemiology to the lowest.