稳心颗粒联合倍他乐克治疗冠心病心律失常疗效观察

Clinical Observation of Wenxin Granules Combined with Betaloc for Arrhythmia of Coronary Heart Disease

目的:观察在常规药物基础上加用稳心颗粒联合倍他乐克治疗冠心病心律失常的临床效果。方法:选择68例冠心病心律失常患者为研究对象,随机分为观察组和对照组各34例,对照组使用常规治疗配合倍他乐克治疗,观察组在对照组基础上加稳心颗粒治疗,2组均用药4周。对2组患者疗效进行分析,观察治疗前后心功能与血液流变学的变化。结果:总有效率观察组为91.18%,对照组为70.59%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组心排出量(CO)、心脏指数(CI)、射血分数(EF)均治疗前升高(P<0.01),观察组各指标值均高于对照组(P<0.01)。2组全血黏度(低切)、全血黏度(高切)、血浆黏度、纤维蛋白原均较治疗前降低(P<0.01),观察组各项指标值均低于对照组(P<0.01)。结论:在常规药物基础上加用稳心颗粒联合倍他乐克治疗冠心病心律失常疗效确切,可有效改善心功能,缓解症状。

Objective：To observe curative effect of Wenxin Granules combined with betaloc in treating arhythmia of coronary heart disease.Methods：Selected 68 patients with arrhythmia of coronary heart disease,divided them into the observation group and the control group,34 cases in each.The control group was given routine treatment combined with betaloc,the observation group was given the therapy of Wenxin Granules based on the treatment of the control group.Treatment last for 4 weeks.Analysed curative effect of the two groups,and observed changes of cardiac function and hemorheological parameters before and after treatment.Results：The total effective rate of the observation group and the control group was 91.18%and 70.59%,respectively,the difference being significant（P〈0.05）.All the above indexes of the observation group were higher than those in the control group（P〈0.01）.After treatment,cardiac output（CO）,cardiac index（CI）,ejection fraction（EF） were higher than those before treatment（P〈0.01）.Whole blood viscosity（low shear）,Whole blood viscosity（high shear）,plasma viscosity,fibrinogen were lower than those before treatment（P〈0.01）.All these indexes of the observation group were lower than those in the control group（P〈0.01）.Conclusion：Wenxin Granules combined with betaloc has a good efficacy in treating arrhythmia of coronary heart disease,can improve cardiac function effectively and relieve symptom.