醒脑静注射液联合脑神经营养剂治疗急性脑梗死临床观察

Clinical Observation on Xingnaojing Injection Combined with Nutritional Agents for Cranial Nerves in Treating Patients with Acute Cerebral Infarction

目的:观察醒脑静注射联合脑神经营养剂治疗急性脑梗死的临床疗效。方法:选取76例急性脑梗死患者,以随机抽签法分为对照组和观察组各38例,对照组单纯采用脑神经营养剂治疗,观察组在对照组用药基础上加用醒脑静注射液治疗。比较2组临床疗效,治疗前后脑电图异常程度、美国国立卫生院神经功能缺损评分(NIHSS评分)及血液流变学指标的变化。结果:治疗2周后,观察组临床疗效总有效率高于对照组(P<0.05)。2组脑电图异常程度均较治疗前改善,观察组优于对照组(P<0.05);2组NIHSS评分均较治疗前降低(P<0.05),观察组NIHSS评分低于对照组(P<0.05);2组血液流变学指标水平均低于治疗前(P<0.05),观察组各指标水平均低于对照组(P<0.05)。结论:醒脑静注射联合脑神经营养剂治疗急性脑梗死可有效消除脑电图异常、降低神经功能损伤程度,并有助于改善血液流变学,疗效确切。

Objective：To observe curative effect of Xingnaojing injection combined with nutritional agents for cranial nerves in treating patients with acute cerebral infarction.Methods：Selected 76 patients with acute cerebral infarction,divided them into the observation group and the control group randomly,38 cases in each.The control group was given the therapy of nutritional agents for cranial nerves,the observation group was given the therapy of Xingnaojing injection based on the treatment of the control group.Compared changes of curative effect,abnormal degree of electroencephalogram（EEG）,National Institute of Health Stroke Scale（NIHSS） scores,and level of hemorheological parameters of the two groups before and after treatment.Results：After 2 weeks treatment,the total effective rate of curative effect in the observation group was higher（P〈0.05）.Abnormal degree of EEG was improved.The improvement in the observation group were better than those in the control group（P〈0.05）.NIHSS scores and levels of hemorheological parameters of the two groups were both lower than those before treatment.NIHSS scores and levels of all indexes in the observation group were lower than those in the control group（P〈0.05）.Conclusion：The combination usage of Xingnaojing injection and nutritional agents for cranial nerves in treatment of acute cerebral infarction can eliminate abnormal of EEG,decrease neurologic deficits,improve level of hemorheological parameters and has a good efficacy.