中西医结合治疗小儿腺病毒性肺炎56例临床观察

Clinical Observation of Integrated Chinese and Western Medicine in Treating Children with Adenovirus Pneumonia:A Report of 56 cases

目的:观察中西医结合治疗痰热壅肺型小儿腺病毒性肺炎(AP)的临床疗效。方法:选取56例痰热壅肺型AP患儿为研究对象,随机分为治疗组和对照组各28例。对照组给予利巴韦林注射液与丙种球蛋白(IVIG)治疗,治疗组在对照组的用药基础上联合自拟肺炎1号方治疗。观察2组临床疗效,以及生活质量的改善情况;比较2组持续发热时间、住院时间和不良反应发生率。结果:治疗后,治疗组的临床疗效优于对照组(P<0.01),持续发热时间和住院时间均短于对照组(P<0.01,P<0.05),SF-36评分高于对照组(P<0.05)。治疗期间,治疗组的不良反应发生率为14.29%,低于对照组的21.43%,差异无统计学意义(P>0.05)。结论:中西医结合治疗小儿痰热壅肺型AP,可有效改善患儿的症状、体征,缩短患儿的持续发热时间和住院时间,提高生活质量,临床疗效优于单纯使用西药治疗,且不良反应少,值得临床借鉴。

Objective：To observe the clinical effect of integrated Chinese and western medicine in treating children with adenovirus pneumonia（AP） with phlegm-heat obstructing lung syndrome.Methods：Selected 56 cases of AP children with phlegm-heat obstructing lung syndrome as study objects,and divided them into the treatment group and the control group randomly,28 cases in each group.The treatment of ribavirin injection and gamma globulin（IVIG） was given to both groups,and the treatment group received additional treatment of self-made pneumonia No.Ⅰ recipe.Observed the clinical effect and improvement of quality of life,and compared continuous fever time,hospitalization time and adverse reaction in both groups.Results：After treatment,the clinical effect was better in the treatment group than in the control group（P〈0.01）,continuous fever time and hospitalization time in the treatment group were both shorter than those in the control group（P〈0.01,P〈0.05）,and SF-36 scores in the treatment group were higher than those in the control group（P〈0.05）.During treatment,the incidence of adverse reaction in the treatment group was 14.29%,being shorter than 21.43%in the control group（P〈0.05）,and there was no statistical significance（P〉0.05）.Conclusion：The therapy of integrated Chinese and western medicine for AP children with phlegm-heat obstructing lung syndrome can effectively improve symptoms,physical signs and quality of life,and shorten their continuous fever time and hospitalization time.Its has better clinical effect than the treatment of pure western medicine.It has little adverse reaction and is worth to use for reference.