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恶性胶质瘤的基因异常与治疗 被引量:12

Gene abnormality and gene therapy of malignant gliomas
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摘要 胶质瘤的形成与发展是一个复杂的过程,癌基因的激活、过表达或扩增以及抑癌基因的缺失或突变失活,均可导致细胞增殖、分化和凋亡调节通路的异常.胶质瘤的病理级别越高,累积的分子遗传学改变也越多.
出处 《中华神经外科疾病研究杂志》 CAS 2002年第3期193-196,共4页 Chinese Journal of Neurosurgical Disease Research
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