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NKG2D-NKG2D配体系统抗肿瘤作用研究进展

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摘要 肿瘤的免疫治疗已经成为抗肿瘤治疗中的一个重要策略,越来越多的证据表明,NKG2D-NKG2D配体系统在机体的抗肿瘤免疫中发挥着重要作用。本文对NKG2D及其配体的表达、调节、信号传导、免疫治疗作一综述。
作者 张世魁 李景艳 梅家转
机构地区 郑州人民医院肿瘤内科
出处 《新乡医学院学报》 CAS 2017年第1期79-82,共4页 Journal of Xinxiang Medical University
关键词 NKG2D NKG2D配体 肿瘤免疫治疗 抗肿瘤
分类号 R392.12 [医药卫生—免疫学] R730.51 [医药卫生—肿瘤]
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  • 1Parrish-Novak J,Dillon SR,Nelson A. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function[J].Nature,2000.57-63.
  • 2Monteleone G,Pallone F,Macdonald TT. Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease[J].Cytokine & Growth Factor Reviews,2009.185-191.
  • 3Zhao MF,Deng Q,Li YM. Interleukin 21 enhances the expansion and anti-tumor cytotoxic activity of cytokine-induced killer cells derived from both peripheral blood and cord blood in vitro[C/OL]//ASH annual meeting[J].Blood,2007.4887.
  • 4Hashmi MH,Van Veldhuizen PJ. Interleukin-21:updated review of Phase Ⅰ and Ⅱ clinical trials in metastatic renal cell carcinoma,metastatic melanoma and relapsed/refractory indolent nonHodgkin's lymphoma[J].Expert Opinion on Biological Therapy,2010.807-817.
  • 5Andorsky DJ,Timmerman JM. Interleukin21:biology and application to cancer therapy[J].Expert Opinion on Biological Therapy,2008.1295-1301.
  • 6Davis ID,Brady B,Kefford RF. Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage Ⅳ malignant melanoma without prior treatment:a phase Ⅱ a trial[J].Clinical Cancer Research,2009.2123-2129.
  • 7Meazza R,Azzarone B,Orengo AM. Role of commongamma chain cytokines in NK cell development and function:perspectives for immunotherapy[J].Journal of Biomedicine and Biotechnology,2011.861920.
  • 8Coquet JM,Kyparissoudis K,Pellicci DG. IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production[J].Journal of Immunology,2007.2827-2834.
  • 9Vemeris MR,Komacker M,Mail(a)nder V. Resistance of ex vivo expanded CD3 + CD56 + T cells to Fas-mediated apoptosis[J].Cancer Immunology Immunotherapy,2000.335-345.
  • 10Takaki R,Hayakawa Y,Nelson A. IL-21 enhances tumor rejection through a NKG2D-dependent mechanism[J].Journal of Immunology,2005.2167-2173.

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新乡医学院学报
2017年 第1期

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