精神病患者血液流变学指标的变化及影响因素

Changes and influencing factors of hemorheology indexes in patients with mental disease

目的检测精神病患者血液流变学的相关指标,以便了解长期住院的精神分裂症患者血黏度的变化及其影响因素。方法选取天津市安宁医院长期住院的精神分裂症患者90例为研究组及血液流变学相关指标的检测(包括全血高切、低切还原黏度血浆黏度,红细胞压积)进行比较分析。结果研究组血黏度的相关指标明显高于对照组差异有统计学意义(P<0.05),但红细胞压积80例健康对照组(排除躯体疾病)采用普利生锥板式全自动血流变分析仪对两组进行比较差异无统计学意义(P>0.05)。结论长期住院的精神分裂症患者的血液流变学的一些相关指标明显高于正常对照组,说明血液流变学相关指标的检测对精神科疾病具有一定的临床应用价值,应引起临床医生的高度注意。

Objective Related indexes of blood rheology in patients with mental disorders in order to understand changes of blood viscosity and its influencing factors in schizophrenic patients with long-term.Methods There were 90 inpatients（research group） and 80 normal controls（exclusion of somatic diseases） entered into this study adopted with LBY-N6 full automatic blood rheology analyzer（include：the whole of blood reduction viscosity,low shear viscosity of whole blood,plasma viscosity,HCT） and carried on the comparative analysis.Results The blood viscosity of the study group was significantly higher than the control group,the difference was statistically significant（P〈0.05）,but there was no significant difference in HCT（P〈0.05）.Conclusion Related indexes oi schizophrenic patients in long-term hospitalization of blood rhelogy were significant higher than the control group.The detection of related indexes of blood rheology to the psychiatric disease has certain clinical application.The attention of clinicians should be aroused.