胎儿侧脑室轻度增宽的临床价值

Clinical value of fetuses with mild ventriculomegaly

目的探讨超声诊断胎儿侧脑室轻度增宽的临床预后。方法回顾性分析71例妊娠期超声诊断的胎儿侧脑室10~12 mm病例,部分病例产前诊断胎儿染色体分析或核磁共振(MRI)检查,定期进行超声复查,并对所有病例进行随访。结果71例侧脑室增宽病例36例(50.70%)接受染色体检查,8例(11.27%)行无创DNA检测,44例中染色体异常1例(2.27%);28例在产前或产后进行了MRI的检查,均未见其他异常;65例(91.55%)正常分娩,其中63例(96.92%)随访正常。结论产前超声检查能够敏感地检出轻度侧脑室增宽的胎儿,孤立性轻度侧脑室增宽者染色体异常概率较低,预后较好。

Objective To explore the clinical prognosis of fetuses with mild ventriculomegaly diagnosed by ultrasonography.Methods Seventy-one pregnant women were recruited retrospectively,all of the fetuses were diagnosed as ventriculomegly（10-12 mm）by sonography.Fetal karyotyping or MRI was performed for some cases,and all the fetuses were followed up.Results Among seventy-one cases,36 cases（50.70%） underwent karyotyping,8 cases（11.27%） underwent noninvasive DNA test,one case（2.27%） was diagnosed as chromosomal abnormality;28 fetuses were followed up by MRI,no other abnormality was found;65 cases（91.55%） adopted vaginal delivery,and 63 cases（96.92%） were normal during follow-up.Conclusion Ultrasonography is an effective method for prenatal diagnosis of mild ventriculomegly.The incidence rate of abnormal karyotype in mild vetriculomegaly cases is very low,and the prognosis is good.