FMC化疗方案联合益气健脾活血汤治疗中晚期胃癌临床观察

Clinical Observation on FMC Chemotherapy Regimen Combined with YiqiJianpiHuoxue Tang for Advanced Gastric Cancer

目的:观察FMC化疗方案联合益气健脾活血汤治疗中晚期胃癌的临床效果及其安全性。方法:将符合纳入标准的96例中晚期胃癌患者按随机数字表法分为2组各48例。对照组患者接受FMC化疗方案治疗,观察组在对照组治疗方案的基础上联合益气健脾活血汤治疗,对2组患者治疗后效果及毒副作用发生情况进行观察。结果:观察组治疗后有效率43.75%,对照组22.92%,2组比较,差异有统计学意义(P<0.05);观察组治疗后毒副反应发生率均低于对照组,差异有统计学意义(P<0.05)。结论:中晚期胃癌接受FMC化疗方案联合益气健脾活血汤治疗效果满意,不仅能提高肿瘤控制效果,也能缓解症状,降低毒副反应发生率,提高患者生存质量,利于远期预后。

Objective： To observe the clinical effect and safety of the therapy of FMC chemotherapy regimen combined with Yiqi Jianpi Huoxue tang in treating advanced gastric cancer. Methods： Divided 96 cases of patients with advanced gastric cancer according with standard into two groups randomly,48 cases in each group. The two groups were both treated with FMC chemotherapy regimen,but the observation group additionally received Yiqi Jianpi Huoxue tang for treatment. Observed the curative effect and toxic side effects in both groups after treatment. Results：The total effective rate after treatment was 43.75% in the observation group and22.92% in the control group, the significant difference being found in the comparison between two groups（P〈0.05）. The incidence of toxic side effect of the observation group after treatment was lower than that of the control group,the difference being significant（P〈0.05）. Conclusion： The effect of patients with advanced gastric cancer receiving FMC chemotherapy regimen combined with Yiqi Jianpi Huoxue tang is satisfying. This therapy can not only enhance the effect of tumor control, but also relieve symptoms, reduce the incidence of toxic side effect and elevate patients’ life quality, which is beneficial to long-term prognosis.