期刊文献+

注射用兰索拉唑联合美罗培南致严重血小板减少症1例 被引量:9

One case of serious thrombocytopenia induced by lansoprazole and meropenem for injection
原文传递
导出
摘要 兰索拉唑(1ansoprazole)为苯并咪唑类衍生物,属于质子泵抑制剂。其分布于胃黏膜壁细胞的酸性环境后.转变为有活性的代谢物。这种代谢物与酸生成部位的H^+-K^+-ATP酶的巯基结合,通过抑制H^+-K^+-ATP酶的活性而抑制酸分泌。主要用于治疗口服疗法不适用的伴有出血的消化性溃疡和预防应激性溃疡。
作者 邓艳辉 许静 汪燕 DENG Yan-hui XU Jing WANG Yan(Department of Pharmacy, the Third Affiliated Hospital to Southern Medical University, Guangzhou GUA NGDONG 510630, China)
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2017年第1期56-58,共3页 Chinese Journal of New Drugs and Clinical Remedies
关键词 兰索拉唑 美罗培南 血小板减少 药物不良反应 lansoprazole meropenem thrombocytopenia adverse drug reactions
  • 相关文献

参考文献3

二级参考文献50

  • 1张俊忠.美罗培南诱发严重血小板减少症1例[J].药物流行病学杂志,2004,13(6):350-350. 被引量:15
  • 2方强,石应康,王兰兰,李立新,姜虹.低剂量鱼精蛋白拮抗肝素围体外循环期血浆肝素浓度变化与凝血功能损害[J].实用医学杂志,2005,21(2):133-135. 被引量:11
  • 3杜娟,钱晓萍,胡文静,刘宝瑞.健择化疗后免疫机制介导的血小板减少症[J].现代医学,2007,35(4):325-326. 被引量:7
  • 4van den Bemt PM, Meyboom RH, Egberts AC. Drug induced immune thrombocytopenia[J]. Drug Saf, 2004,27 ( 15 ) : 1243 1252.
  • 5Kaufman DW, Kelly JP, Johannes CB, et al. Acute thrombo cytopenic purpura in relation to the use of drugs[J]. Blood. /993,82(9) :2714-2718.
  • 6Aster RH,Curtis BR, McFarland JG, et al. Drug induced im- mune thrombocytopenia: pathogenesis, diagnosis, and man agement[J]. J Thromb Haemost,2009,7(6) :911-918.
  • 7Visentin GP,Newman PJ, Aster RH. Characteristics of qui- nine and quinidine-induced antibodies specific for platelet glyco proteins Ⅱb and Ⅲa[J]. Blood, 1991, 77(12) : 2668-2676.
  • 8Bougie DW,Wilker PR, Aster RH. Patients with quinine in- duced immune thrombocytopenia have both"drug-dependem" and "drug specific" antibodies[J]. Blood,2006,108:922-927.
  • 9Perdomo J, Yah F, Ahmadi Z, el at. Quinine induced lhrom boeytopenia: drug-dependent GPIb/IX antibodies inhibil megakaryoeyte and proplatelet production in vitro[J]. Blood, 2011,117(22):2275-2286.
  • 10Bougie DW,Wilker PR,Wuitschick ED, et al. Acute thrombo cytopenia after treatment with tirofiban or eptifibatide is associ ated with antibodies specific for ligand-occupied GPⅡb/Ⅲa[J]. Blood, 2002, 100 : 2071-2076.

共引文献82

同被引文献95

引证文献9

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部