鼻吸气压对慢性心力衰竭患者吸气肌强度的评价及其与膈肌形态学的关系研究

Research of Evaluation of Inspiratory Muscle Strength by Sniff Nasal Inspiratory Pressure in Patients with Chronic Heart Failure and ITS Relationship between Diaphragm Muscle's Morphological

目的探讨鼻吸气压(SNIP)对慢性心力衰竭(CHF)患者吸气肌强度的评价及其与膈肌形态学的关系。方法选取在我院确诊的71名CHF患者(观察组)和74名健康人(对照组)为研究对象,检测入选对象的SNIP、最大口腔吸气压(MIP)、膈肌移动度(DE)和膈肌厚率。结果 CHF患者的SNIP、MIP、DE和膈肌厚率均比对照组低,差异有统计学意义(P<0.05);SNIP与MIP呈正相关(r=0.994,P<0.05),与DE、膈肌厚率呈正相关性(r=0.715、0.754,P<0.05)。结论 SNIP可以间接评价CHF患者吸气肌强度,SNIP与MIP、膈肌厚率和DE有相关性,在一定程度上可以反映CHF对膈肌形态学的影响。

OBJECTIVE To study the evaluation of inspiratory muscle strength by sniff nasal inspiratory pressure in patients with chron- ic heart failure and the relationship between diaphragm muscle＇s morphological. METHODS Selecting 71 patients with CHF （observa- tion group） diagnosed in our hospital, and 74 healthy people （control group） as the research object, and test all of the people SNIP, the largest oral inspiratory pressure （MIP） and the diaphragm excursion（DE） and diaphragm thickness ratio. RESULTS Observation group＇s SNIP, MIP, DE and diaphragm thickness were significantly lower than the control group, the difference was statistically signif- icant （P〈0.05）. SNIP and MIP were positively correlated（r=0.994, P〈0.05）, while showed positivelycorrelation with DE and dia- phragm thickness rate（r=0.715, 0.754, P〈0.05）. CONCLUSION SNIP could be the indirect assessment of inspiratory muscle strength in patients with CHF, and it showed relevance with MIP, diahpragm and DE, so it might reflect the influence of the CHF to dia- phragmatic muscle morphology.