饮食限制延缓衰老的研究进展

The possible role of dietary restriction in anti-aging:a review on research progress

目前随着经济发展及生活水平的不断提高,中国老龄化情况日益严重,各种衰老相关疾病的发病率也呈直线上升。因此,寻找有效的延缓衰老方法、预防老年病的发生越来越受到人们的关注。近几年研究表明,饮食限制(DR)可以有效地延长哺乳动物的寿命,同时延缓老年病的发生。在避免营养不良的前提下对饮食摄入进行限制,现今已成为抗衰老领域的一大热门方向。本文就DR在延缓衰老中的作用及其可能机制的研究进展作一综述。

Nowadays, along with the development of economy and rising of the living standards, the status of population aging gets more and more severe in China. Since the incidence of age-related diseases straights up, more and more attention was paid to the search for effective anti-aging methods and prevention of geriatric diseases. In recent researches, dietary restriction （DR） is confirmed to prolong the lifespan in mammal effectively, and to prevent the age-related diseases. In the context of avoiding malnutrition, proper DR has been a hot topic in anti-aging research. This article reviewed the roles and possible mechanisms of DR in anti-aging.