脑出血时脑脊液变化对磁感应相移信号的影响

Effect of cerebrospinal fluid changes on magnetic induction phase shift signal in intracerebral hemorrhage

目的:研究脑出血时脑脊液变化对磁感应相移信号的影响。方法:选取新西兰大白兔自体血注射模拟脑出血模型,并利用目前成熟的磁共振影像学手段获取脑脊液体积变化并分析其代偿过程,之后通过自动分割算法对图像进行分割,得到脑脊液信号,并与测量得到的磁感应相移信号结合,利用SPSS软件对其相关性进行分析。结果和结论:依据实验结果得出脑出血过程中脑脊液体积和磁感应相移信号具有较强相关性的结论,具体表现为出血体积增加,脑脊液体积和磁感应相位移信号均减小。

Objective To investigate the effects of cerebrospinal fluid（CSF） changes on magnetic induction phase shift（MIPS）signal during the intracerebral hemorrhage（ICH）. Methods The autologous blood injection of New Zealand White Rabbit was selected as ICH simulation model. The magnetic resonance imaging was used to obtain the CSF changes and to analyze the compensatory process, and the automated segmentation algorithm was used to segment the image and to obtain the CSF signal which was combined with measured MIPS signal. SPSS software was adopted to analyze the correlation among the bleed volume, CSF volume and MIPS signal. Results and conclusion During the ICH, CSF has a strong correction with MIPS signal, specifically, bleeding volume increases while CSF volume and MIPS signal decreases.