《中国伏立康唑个体化用药指南》制订过程的探讨

Discussion of development of Chinese Practice Guideline for Individualized Medication of Voriconazole

中国伏立康唑个体化用药指南的指南证据收集与分级、患者偏好与价值观调查及经济学分析全部完成。指南共识专家组应用三轮德尔菲法和推荐等级的评估,制定和评价(GRADE)网格法,进行推荐意见共识。最终共38条推荐意见达成共识,共识率50.7%。指导委员会专家共批准通过了27条推荐意见,确定了指南推荐意见初稿。

Collection and rating of evidence,survey of patients ＇ preference and value and economic evaluation of the Practice Guideline for Therapeutic Drug Monitoring of Voriconazole have been finished. The Guideline Consensus Panel reached consensus of the recommendations by 3 rounds Delphi and Grading of Recommendations Assessment,Development and Evaluation grid method. Consensus of 38 recommendations was reached, with a consensus percentage of 50. 7%. Twenty seven recommendations were finalized and approved by the Guideline Steering Committee. Draft recommendations were generated.