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The dynamics of adult neurogenesis in human hippocampus 被引量:4

The dynamics of adult neurogenesis in human hippocampus
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摘要 The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans.At least two discrete places house stem cells for generation of neurons in adult brain. These are olfactory system and the hippocampus. In animals, newly generated neurons have been directly or indirectly demonstrated to generate a significant amount of new neurons to have a functional role. However, the data in humans on the extent of this process is still scanty and such as difficult to comprehend its functional role in humans. This paper explores the available data on as extent of adult hippocampal neurogenesis in humans and makes comparison to animal data. The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans.At least two discrete places house stem cells for generation of neurons in adult brain. These are olfactory system and the hippocampus. In animals, newly generated neurons have been directly or indirectly demonstrated to generate a significant amount of new neurons to have a functional role. However, the data in humans on the extent of this process is still scanty and such as difficult to comprehend its functional role in humans. This paper explores the available data on as extent of adult hippocampal neurogenesis in humans and makes comparison to animal data.
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第12期1869-1883,共15页 中国神经再生研究(英文版)
基金 supported by the Consortium for Advanced Research Training in Africa(CARTA).CARTA is jointly led by the African Population and Health Research Center(APHRC)and the University of the Witwatersrand funded by the Wellcome Trust(UK)(Grant No.087547/Z/08/Z) the Department for International Development(DfID)under the Development Partnerships in Higher Education(DelPHE),the Carnegie Corporation of New York(Grant No.B 8606) the Ford Foundation(Grant No.11000399) Google.Org(Grant No.191994) Sida(Grant No.54100029) Mac Arthur Foundation(Grant No.10-95915-000-INP) British Council
关键词 adult neurogenesis neuron neuronal stem cell proliferation differentiation neuronal turn-over hippocampus human neurogenesis adult neurogenesis neuron neuronal stem cell proliferation differentiation neuronal turn-over hippocampus human neurogenesis
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