补片技术修复肩袖损伤的应用研究

Progress in Application of Reinforced Patch Technology for Rotator Cuff Tears

肩袖巨大撕裂单纯手术缝合后复发率高达50%~70%,学者们提出肩袖补片修补可增加肩袖生物力学性能。采用哪种材料的补片更有效地恢复其生理功能成为当今研究热点。肩袖补片分为人工合成(不可降解型,可降解型)和生物材料(自体或同种异体组织,异种异体材料)两种类型。人工合成材料具备载体力学强度,但术后免疫反应重;生物材料排异反应轻,生物活性转归好,降解率调控灵敏,但最大抗拉强度较低。本文综述目前肩袖补片应用过程中的常见问题和进展。

With an increasing higher failure rate from 50% to 70% after simple sutured surgery for rotator cuff tears,scholars have put forward the patch augmented biomechanics for healing massive tears. Research hotspots lie in the material structural and physiological properties. There are two types of rotator cuff patches,which are synthetic materials（ non-degradable and degradable type） and biological rotator cuff patch（ autologous or allogeneic tissue,xenogeneic material）. The synthetic materials rotator cuff patch is able to provide powerful biomechanics but has severe immune rejection,and the biomaterials patch provides excellent histological reconstruction in rotator cuff and accurate regulation of biological activity of metabolic degradation but lower biomechanical maximum tensile strength. This article reviewed the current common problems and progress in the application of the rotator cuff patches.