双原发肺癌的胸外科治疗结局和长期生存率探讨

Discussion on the Treatment Outcome and Long-term Survival Rate of Patients with Double Primary Lung Cancer

目的探讨双原发肺癌(Double primary lung cancer,DPLC)的胸外科治疗结局和长期生存率。方法方便选取2005年5月—2010年5月该院收治的65例患者为研究对象,回顾分析其临床资料,观察其手术治疗结局及生存率。结果该组65例患者,同一肺叶25例,不同肺叶40例,同一肺叶与不同肺叶手术切除率均为100%,但二者的根治切除率比较,差异有统计学意义(P<0.05);术后并发症发生率为32%(21/65),术后1、3年与5年生存率分别为53%、31%与21%。结论双原发肺癌患者经手术治疗,疗效确切,降低了并发症发生几率,延长了患者生存时间。

Objective To investigate the treatment outcome and long-term survival rate of primary lung cancer DPLC（Double） in the Department of thoracic surgery of double primary lung cancer（primary lung cancer）. Methods Convenient selection 65 patients admitted to our hospital from May 2005 to May 2010 were selected as the research object. The clinical data were retrospectively analyzed to observe the outcome and survival rate of the patients. Results The group of 65 patients, 25 cases of the same lobe, 40 cases of different lobes, in the same lobe and lobe resection rate were 100%, but both the radical resection rate, the difference is statistically significant（P〈0.05）; postoperative complication rate was 32%（21/65）. After 1year, 3 years and 5 years survival rate of 53%, 31% and 21%, respectively. Conclusion Double primary lung cancer patients by surgical treatment, the exact effect, reduce the incidence of complications, prolong the survival time of patients.