卡培他滨与调强放疗用于食管癌术后纵隔淋巴结转移中的临床效果

Clinical Effect of Applying Capecitabine and Intensity Modulated Radiation Therapy to Treat Mediastinal Lymph Node Metastasis After Esophageal Cancer Operation

目的探讨卡培他滨与调强放疗治疗食管癌术后纵隔淋巴结转移中的临床效果。方法方便选取2014年4月—2016年5月该院收治的食管癌术后纵隔淋巴结转移患者60例为对象,分为对照组(n=29)采用单纯强调化疗,治疗组(n=31)采用卡培他滨与调强放疗,比对两组疗效。结果治疗组缓解有效率为96.77%,对照组缓解有效率为65.52%;且治疗组1年生存率90.63%和2年生存率58.06%均高于对照组1年生存率65.52%和2年生存率34.48%,两组差异有统计学意义(P<0.05)。结论卡培他滨与调强放疗应用于食管癌术后纵隔淋巴结转移中的治疗效果显著,有助于缓解患者病情,提高其生存率,安全性高,值得推广。

Objective To explore the clinical effect of applying capecitabine and intensity modulated radiation therapy to treat mediastinal lymph node metastasis after esophageal cancer operation. Methods Convenient selection 60 patients with mediastinal lymph node metastasis after esophageal cancer operation treated in our hospital from April 2014 to May 2016 were selected as research objects, and were divided into two groups. The control group（n=29） only received intensity modulated radiation therapy, and the treatment group（n=31）was treated with capecitabine and intensity modulated radiation therapy. The efficacy of two groups was compared. Results The treatment group alleviate the effective rate was 96.77%, the control level effective rate was 65.52%; And the treatment group 1 year survival rate was 90.63% and 2 year survival rate was58.06% higher than control group 1 year survival rate was 65.52% and 2 year survival rate was 34.48%, comparable to the two groups（P〈0.05）. Conclusion Applying capecitabine and intensity modulated radiation therapy to treat mediastinal lymph node metastasis after esophageal cancer operation not only has evident treatment effect and helps to relieve the disease condition of patients, but also can improve the survival rate and is safe, which is worthy of promotion.