15594例受血者中输血不良反应相关因素及预防措施分析

Analysis of Related Factors and Preventive Measures of the Adverse Reaction of Blood Transfusion in 15 594 Cases

目的通过对输血不良反应的调查,探讨输血不良反应相关因素及有效降低输血不良反应的措施。方法回顾性分析15 594例受血者发生输血不良反应与年龄、性别、输血史、病种、输注的血液成分、不使用白细胞过滤器输注、反应类型等的关系。结果在15 594例受血者中,输血不良反应35例,反应率为0.22%:输血不良反应的发生与年龄、女性、输血史、内科及妇产科受血者、不使用白细胞过滤器输注等因素的关联有统计学意义(P<0.05);输注不同血液制品与反应类型的关联无统计学意义(P>0.05);反应类型以非溶血性发热反应为主,发生率65.72%。结论年龄、性别、输血史、病种、不使用白细胞过滤器输注等因素与输血不良反应的发生相关;严格掌握输血指证,加强预防和监测是保证用血安全的重要措施。

Objective Explore the relative factors and effective resolution for adverse transfusion reaction through the investigation in our hospital. Method sThe relationship of blood transfusion adverse reaction and age,sex,history of blood transfusion,disease,transfusion of blood components,non use of white blood cell filter and the reaction types were studied in 15594 patients. Results In 15 594 blood recipients there were 35 cases of adverse transfusion reaction （0.22%）. There was a significant correlation between the occurrence of adverse transfusion reactions and the factors of age,gender （female）,history of blood transfusion,internal medicine,Gynecology and Obstetrics,and the disuse of white blood cell filter（0.001〈P〈0.05）; Infusion of different blood products and reaction type shows no statistical difference （P〉0.05）. The reaction types were mainly non hemolytic febrile reaction,and the incidence rate was 65.72%. Conclusion Factors like age,gender,history of blood transfusion,disease type and disuse of white blood cell filter were associated with the occurrence of adverse transfusion reactions. Strict control of blood transfusion testify,prevention and monitoring are ways ensuring the safety of blood using.