摘要
文章首次报道了一种以2-吲哚酮为底物经Cu(II)催化一步合成靛红的新方法.这种方法以简便的操作和无需添加化学计量的氧化剂为主要特色,反应中的氧气不仅作为反应试剂同时也充当氧化剂,从而使这种方法更加绿色和实用.通过核磁共振氢谱、核磁共振碳谱对产物的结构进行了表征.另外文中还提出了可能的反应机理.
A copper（II）-catalyzed one-step synthesis of isatin from 2-oxindole has been reported for the first time.Operational simplicity and no addition of any other stoichiometric oxidant are the key features of this protocol.Molecular oxygen is employed as a reagent and the sole oxidant,thus making this protocol more green and practical.The structure of product were characterized by 1 H NMR spectra and 13 C NMR spectra.In addition,aplausible mechanism of this reaction was proposed.
作者
于静文
宋璐娜
YU Jingwen SONG Luna(Jinci College of Shanxi Medical University, Department of Basic Medical Sciences, Taiyuan 030025, Chin)
出处
《太原师范学院学报（自然科学版）》
2016年第4期77-80,共4页
Journal of Taiyuan Normal University:Natural Science Edition
基金
山西医科大学校级科研基金项目(02201540)
关键词
合成方法
铜
2-吲哚酮
氧化
靛红
synthetic method
copper
2-oxindole
oxidation
isatin
