循环肿瘤细胞的检测及其临床应用

Detection of circulating tumor cells and its clinical application

循环肿瘤细胞（CTC）是一种自发或因手术、穿刺等引起的从肿瘤病灶脱落入血的恶性肿瘤细胞。近年来，随着对CTC研究的不断深入，其检测方法也逐渐多样化。临床上，CTC作为新兴的生物学标志物，在肿瘤的诊断、疗效监测和预后评估中起着非常重要的作用。文章介绍了目前CTC富集和分析技术，并阐述CTC与肿瘤之间的关系。

Circulating tumor cell （CTC） is a kind of malignant tumor cells shed from the primary tumor into the circulation caused by spontaneity or surgical operation and puncture. With the development of CTC analysis recently, the detection methods have been gradually diversified. As a new biomarker, CTC plays a significant role in the diagnosis, therapeutic effect monitoring and prognosis of tumors. This paper mainly introduces the enrichment and analysis technology of CTC, and explore the relationship between CTC and tumors.