食管贲门黏膜撕裂综合征诊治分析

Diagnosis and treatment of mallory-weiss syndrome

目的探讨食管贲门黏膜撕裂综合征（MWS）的诊治现状。方法回顾性分析沈阳军区总医院自2011年6月至2016年6月收治的96例MWS患者的临床资料。分析本组患者的年龄与性别、发病诱因及内镜表现。结果本组患者中,男性发病率高于女性;40~59岁的发病率较其他年龄段高。发病诱主要为酗酒,其次为口服阿司匹林。撕裂部位为食管下端到贲门部,均为纵形撕裂。本组患者经过积极治疗,93例病愈出院,3例死亡。结论 MWS是临床上较常见的消化道出血病因;减少酗酒及避免长期应用阿司匹林是避免MWS的主要手段;内科药物治疗配合胃镜下微创技术是治疗MWS的有效治疗方法。

Objective To investigate the clinical characteristic and treatment of mallory-weiss syndrome（ MWS）. Methods A retrospective study was performed on 96 MWS patients received in The General Hospital of Shenyang Military Command from June 2011 to June 2016. The age,gender,induced factors and endoscopic manifestations were analyzed. Results In this group of patients,morbidity rate of male was higher than that of female. The incidence of 40 to 59 years was higher than that of the other age groups. The induced factors were mainly alcoholics and secondly oral aspirin. Tear parts were from lower esophagus to cardiac,and the tear part was longitudinal. Incidence after active treatment,93 cases were discharged from the hospital,and 3 cases died. Conclusion Mallory-weiss syndrome is one of the common clinical gastrointestinal bleeding disease causes. To reduce alcohol abuse,and avoid long-term use of aspirin is the principal means of MWS. Internal medicine medications with therapeutic endoscopy may appear as the reasonable method of treatment for patients with Mallory-weiss syndrome.