降钙素原在新生儿脓毒血症临床治疗中的应用效果评价

Evaluation on application effect of procalcitonin in neonatal pyemia treatment

目的探讨在新生儿脓毒血症临床治疗中降钙素原的作用及效果。方法 60例新生儿脓毒血症患儿,随机分成观察组与对照组,每组30例。分别于治疗前后进行血液检测,两组采用相同类型方法进行治疗,观察组患儿通过降钙素原进行血液检测,对照组患儿通过血培养进行血液检测。观察两组检测效果。结果经过不同方法检测,治疗前观察组的阳性率为100.0%,对照组的阳性率为80.0%,观察组显著高于对照组,差异具有统计学意义(P<0.05)。治疗后观察组的阳性率为26.7%,对照组的阳性率为6.7%,观察组显著高于对照组,差异具有统计学意义(P<0.05)。结论通过降钙素原检查新生儿脓毒血症患儿的血液情况,可以提高检出率,方便及时对新生儿采取针对性的治疗并检测治疗效果,安全有效,值得临床推广。

Objective To explore the effect of procalcitonin in the treatment of neonatal pyemia. Methods A total of 60 children with neonatal pyemia were randomly divided into observation group and control group, with 30 cases in each group. Both groups received same method for treatment. The observation group was detected by procalcitonin, and control group was detected by received blood culture. Blood detection were made before and after treatment, and their detective results were compared between two groups. Results After detection, the observation group had positive rate as 100.0% before treatment, and control group had positive rate as 80.0%. The observation group had a higher positive rate than control group, and difference had statistical significance（P〈0.05）. The observation group had positive rate as 26.7% after treatment and control group had positive rate as 6.7%. The observation group had a higher positive rate than control group, and difference had statistical significance（P〈0.05）. Conclusion Implement of procalcitonin detection shows high detective rate in neonatal pyemia. This method is good for timely and convenient treatment and detection for newborn with security and efficiency, so it is worth clinical promotion.