同一时点酒精依赖患者复饮的多因素研究

Multivariate analysis of re-drinking in alcohol dependence patients at the same time point

目的了解同一时点酒精依赖患者复饮的相关因素,探讨降低复饮的措施。方法 89例戒断治疗出院刚满3个月的酒精依赖患者,按是否复饮分为复饮组(50例)和非复饮组(39例)。用自行设计的酒精依赖患者一般情况调查表、酒精渴求量表及抑郁自评量表对受试的患者进行调查,并比较患者一般情况和临床资料。结果 89例患者均为男性,复饮50例,复饮率为56.2%。两组患者婚姻、职业、家族史、病前性格、文化程度等比较差异均无统计学意义(P>0.05)。两组患者住院次数比较差异均具有统计学意义(P<0.05)。两组患者饮酒史、每日饮酒量、酒精渴求程度及抑郁评分比较差异具有统计学意义(P<0.05)。两组患者经济状况及住院疗效比较差异均无统计学意义(P>0.05)。结论戒酒后同一时点调查酒精渴求程度严重、既往饮酒史长、日饮酒量多及伴抑郁情绪的酒精依赖患者复饮可能性大,有待进一步探讨降低酒精渴求度及酒精复饮评估的方法以降低酒依赖患者的复饮率。

Objective To understand related factors of re-drinking in alcohol dependence patients at the same time point, and to investigate measures for re-drinking decrease. Methods A total of 89 alcohol dependence patients within 3 months after abstinence treatment were divided by re-drinking condition into redrinking group（50 cases） and non re-drinking group（39 cases）. Home-made general situation scale, alcohol craving scale and self-rating depression scale were applied in patients for research. Their general condition and clinical data were compared. Results All the 89 patients were male, with 50 re-drinking cases. Their redrinking rate was 56.2%. There was no statistically significant difference of marriage, occupation, family history, premorbid character, and educational level between the two groups（P〈0.05）. The difference of admission times had statistical significance between the two groups（P〉0.05）. The difference of alcohol intake history, daily alcohol consumption, alcohol craving degree and depression score had statistical significance between the two groups（P〈0.05）. There was no statistically significant difference of financial situation and hospitalized curative effect between the two groups（P〉0.05）. Conclusion At the same time point after abstinence, alcohol dependence patients with severe alcohol craving degree, long alcohol intake history, high daily alcohol consumption and depression have high possibility of re-drinking. Further investigation of measures for reducing alcohol craving degree and evaluating re-drinking is necessary to decrease re-drinking rate in alcohol dependence patients.