药物联合蓝光治疗新生儿黄疸的临床效果分析

Clinical effect of drugs combined with blue ray in the treatment of neonatal jaundice

目的分析并探讨药物联合蓝光治疗新生儿黄疸的临床效果,从而为临床治疗方案的选择提供依据。方法随机选取2013年5月至2016年9月在医院接受治疗的新生儿黄疸患儿100例为研究对象,分为观察组与对照组,每组各50例。观察组给予药物联合蓝光治疗,对照组仅给予药物治疗。观察两组治疗效果及不良反应发生情况。结果观察组治疗有效率为96.00%,对照组治疗有效率为78.00%。观察组治疗有效率明显高于对照组(P<0.05)。观察组皮肤黄染消退时间、平均治疗时间明显短于对照组,且黄疸指数低于对照组。经统计学检验,差异具有统计学意义(P<0.05)。治疗后,观察组发热1例,腹泻2例,不良反应发生率为6.00%。对照组发热1例,腹泻1例,不良反应发生率为4.00%。两组不良反应发生率无显著差异(P>0.05)。结论药物联合蓝光治疗新生儿黄疸的临床效果显著,安全性高,恢复快,值得推广。

Objective To analyze and discuss the clinical effects of drugs combined with phototherapy for neonatal jaundice,and to provide the basis for clinical treatment. Methods 100 cases of neonatal jaundice infants were randomly selected from the patients who got treatment during May 2013 and September 2016 in the hospital. The patients were divided into the observation group and the control group,50 cases in each group. The observation group was treated with combination of drugs and blue light,however,the control group was given drug therapy only. The treatment effect and adverse reaction of the two groups were observed. Results The effective rate of the observation group was 96%,and the effective rate of the control group was 78%. The effective rate of the observation group was significantly higher than that of the control group（ P〈0.05）. In the observation group,the time of skin yellowing,the average treatment time was significantly shorter than the control group,and the jaundice index was lower than that of the control group. The difference was statistically significant（ P〈0. 05）.After treatment,1 case got fever and 2 cases got diarrhea in the observation group,the incidence of adverse reactions was 4%. In the control group,there were 1 case of fever and 1 case of diarrhea,the incidence of adverse reactions was 4%. There was no significant difference in adverse reactions between the two groups（ P〉0. 05）.Conclusions The drug combined with phototherapy in the treatment of neonatal jaundice has significant clinical effect. It is safe and quick recovery,worthy of promotion.