奥曲肽不同应用方式治疗胰腺炎患者90例疗效研究

Clinical effect research of different application methods of octreotide in treatment 90 cases of patients with pancreatitis

目的探讨和分析奥曲肽不同应用方式治疗90例胰腺炎患者的临床效果。方法选取2014年6月~2016年6月期间在我院接受临床治疗的90例胰腺炎患者作为研究对象,随机分为两组,每组45例,对照组患者应用皮下注射奥曲肽的方式进行治疗,研究组患者应用微量注射泵持续注射奥曲肽的方式进行治疗,分析两组患者的效果。结果研究组患者的临床治疗总有效率明显高于对照组患者（P〈0.05）,研究组患者的恢复进食时间、临床症状消失时间、血淀粉酶恢复时间、住院天数明显短于对照组患者（P〈0.05）,研究组患者的不良反应总发生率明显低于对照组患者（P〈0.05）。结论与皮下注射的应用方式相比,使用应用微量注射泵持续注射奥曲肽的应用方式对于胰腺炎患者的临床治疗效果更佳。

Objective To investigate and analyze the clinical effects of different application methods of octreotide in treatment 90 cases of patients with pancreatitis. Methods 90 patients with pancreatitis cured in our hospital from June 2014 to June 2016 were randomly divided into two groups with 45 patients in each group. Patients in control group were treated with subcutaneous injection of octreotide. Patients in study group were treated with microinjection pump with continuous injection of octreotide, and the effects of the two groups were analyzed. ResultsThe total effective rate in study group was significantly higher than that in control group（P〈0.05）. The recovery time, clinical symptom disappearance time, recovery time of amylase and length of hospital stay in study group were significantly shorter than those in control group（P〈0.05）. The overall incidence of adverse reactions in study group was significantly lower than that in control group（P〈0.05）. Conclusion Compared with the application of subcutaneous injection, the application of continuous injection of octreotide by microinjection pump is more effective in the treatment of pancreatitis patients.