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地西他滨联合CAG方案治疗老年急性髓系白血病临床疗效观察 被引量:14

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摘要 目的分析和观察地西他滨联合CAG方案治疗老年急性髓系白血病(AML)临床疗效。方法选择从2012年1月至2015年12月在本院接受治疗的老年急性髓系白血病患者36例,随机分成治疗组和对照组,每组各18例。对照组行CAG方案治疗,治疗组行地西他滨联合CAG方案治疗。观察和对比两组的治疗效果和不良反应发生率。结果与对照组相比,治疗组治疗有效率更高,比较差异具有统计学意义(P<0.05);与对照组相比,治疗组血小板减少发生率较低,但肺部感染、恶心呕吐、发热的发生率较高,比较差异均具有统计学意义(P<0.05)。结论在老年AML的治疗中地西他滨联合CAG方案可显著提高治疗效果,但肺部感染、恶心呕吐、发热等药物不良反应明显增加,高龄患者应慎用。
出处 《齐齐哈尔医学院学报》 2016年第29期3658-3659,共2页 Journal of Qiqihar Medical University
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