活血利水法对原发性肾性水肿的临床作用机制

目的：研究活血利水法对原发性肾性水肿的临床作用机制;方法：2016年3月-10月份在我院接受治疗的原发性肾性水肿患者70例,随机分为治疗组和对照组各35例。对照组以西药百令胶囊常规治疗,治疗组在对照组基础上加活血利水法,疗程3周。结果：经过3周的治疗,患者均有不同程度的好转。其中治疗组患者的病情恢复情况明显的要优于对照组患者。治疗组治愈率为94.3%;对照组治愈率为71.42%。两组比较具有显著性统计学意义（P〈0.05）。治疗组患者心钠素水平（ANP）治疗后与治疗前相比明显的得到提高（P〈0.05）,而对照组患者进行检测治疗前后并没有发生多大变化。结论：活血利水法可能通过提高患者体内的ANP水平,发挥活血化瘀、利水消肿作用。

Objective, The aim is to study the clinical therapeutic effct and mechanism of Huoxue Lishui therapy on the primary renal edema. Methods： Total of 70 patients with primary renal edema in our hospital from March to October 2016 were accepted in this clinical trial. The patients were randomly divided into treatment group and control group consisting of 35 cases each group. In the control group, the patient with primary renal edema were routinly treated with western medicine, while in the treatment group with Huoxue Lishui therapy as well as western medicine routinly for treatment curse of 3 weeks. Results.. After 3 weeks of treatment, all patients had different degree of improvement. Patients in the treatment group （the cure rate was 98.75%） were significantly better than those in the control group （the cure rate was 68.24%） with statistical significance （P〈0.05）. The atrial natriuretic peptide （ANP） in the treatment of before and after treatment compared with significantly improved （P 〈 0.05）, while the control group before and after treatment were detected and did not change much. Conclusion： The promoting blood and diuresis therapy can be helping patients to eliminate edema by raising the level of ANP in patients with primary renal edema.