SPECT/CT融合显像在肺癌患者肋骨病灶良、恶性鉴别诊断中的应用

Application of SPECT/CT Fusion Imaging of the Patients with Lung Neoplasms for Differential Diagnosis of Benign and Malignant Rib Diseases

目的 评价SPECT/CT融合显像在肺癌患者肋骨病变良、恶性鉴别诊断中的应用价值。方法 对2013年3月-2015年3月间在我科行肋骨融合显像的肺癌患者进行随访。结果 69例患者152个病灶符合研究标准,男性例45,女性例24,年龄32-85岁,中位年龄65岁。SPECT/CT融合显像随访诊断总符合率86.84%,其中肯定性诊断为骨转移或良性病灶的102个,诊断符合率89.47%;SPECT骨显像随访诊断总符合率63.16%,其中肯定性诊断为骨转移或良性病灶的75个,诊断符合率78.13%,二者在诊断肺癌患者肋骨骨转移灶和良性病灶准确性方面有统计学差异（X2=4.96,4.13,P﹤0.05）。结论SPECT/CT融合显像可以提高肺癌患者肋骨病变诊断的准确性。

Objective To evaluate the fusion imaging of the patients with lung neoplasms of SPECT/CT for differential diagnosis of benign and malignant rib diseases. Methods The follow-up diagnosis was carried out in the patients with rib fusion imaging in our department from March 2013 to March 2015. Results 152 lesions in sixty-nine patients matched the study criteria. There were 45 male and 24 female patients. Their median age was 65 years old. Of the 69 patients, the coincidence rate of the fusion imaging of SPECT/CT follow-up diagnosis was 86.84%. The rate of diagnose accordance of bone metastasis or the benign was 89.47%, in 102 lesions. The coincidence rate of the bone imaging of SPECT follow-up diagnosis was 63.16 %. The coincidence rate of definite diagnosis of bone metastasis or the benign was 78.13% in 75 lesions.The difference in diagnostic accuracy was statistically significantly between these two methods（x2=4.96, 4.13, P〈0.05）. Conclusion The fusion imaging of SPECT/CT may improve the accuracy of diagnosing the rib diseases.