顺势胰体尾切除对胰腺癌治疗的临床分析

Clinical analysis of antegrade pancreatosplenectomy for curative resection of adenocarcinoma of the left pancreas

目的探讨胰体尾癌根治术中顺行胰体尾切除对胰腺癌治疗的意义。方法对2010年1月到2015年安徽省立医院收治的40例胰体尾部癌患,20例行顺势胰体尾切除,20例行传统胰体尾切除,对两组进行对比分析。结果 RAMPS组在术中淋巴结清扫数目明显高于传统手术组(RAMPS组14.8±5.1个vs.传统手术组10.6±7.3个,P=0.0416)。R0切除率RAMPS组也明显高于传统手术组(RAMPS组18/20 vs.传统手术组12/20,P=0.0280)。RAMPS组5年生存率也高传统手术组。(P=0.0241)。结论顺势胰体尾切除对胰腺癌治疗是安全可行的。

Objective To introduce antegrade pancreatosplenectomy for curative resection of adenocarcinoma of the left pan- creas. Methods From January 2013 to January 2014,20 patients underwent antegrade for curative resection of adenocarcinoma of the left pancreas. 20 patients underwent standard pancreatosplenectomy. We compared the clinicopathologic factors and oncologic outcomes of two groups. Results The R0 rate and retrieved lymph nodes were significant higher in RAMPS group （ P = 0. 0416, P = 0. 0280）. The RAMPS group had longer overall survival than standard group （P = 0. 0280）. Conclusion Antegrade pancreatosplenectomy for curative resection of adenocarcinoma of the left pancreas is favor of the dissection of the posterior pancreatic surface,which is safe and feasible.