澳门地区心房颤动患者的临床调查

The atrial fibrillation in Macao

目的了解目前澳门地区心房颤动（房颤）的临床特点和治疗现状，为进一步研究奠定基础。方法选取澳门山顶医院心脏科门诊就诊的房颤患者，登记患者的人口学特征、临床特征、抗凝及抗心律失常药物治疗情况及并发症发生情况。结果从2014年1月至2014年12月，共有652例患者入选，平均年龄为（72．1±11．5）岁，女320例（49％），年龄≥80岁的患者211例（32．3％），合并高血压患者410例（62．9％），合并血栓栓塞事件患者135例（20．7％）。瓣膜性和非瓣膜性房颤患者分别为180例和472例（27．6％和72．4％）。患者平均CHA2DS2-VASc评分3．2分，CHA2DS2-VASc≥2分的患者519例（79．6％）。接受抗凝治疗的患者257例（54．4％），其中华法林101例（21．4％），非维生素K口服抗凝药156例（33．0％）。结论澳门地区房颤患者平均年龄较大，瓣膜性房颤比例较高。房颤患者接受抗凝治疗比例高，脑卒中的发生率较低。

Objective To describe the baseline characteristics and treatment of atrial fibrillation（AF） patients in Macao and contribute to further studies on AF in future. Methods This retrospective study enrolled all the atrial fibrillation patient consulted at cardiology clinic in the Centro hospitalar Conde de Sao Januario （CHCSJ）, the only one public hospital in Macao. Baseline data included demographics, clinical characteristics and treatments. Results A total of 652 AF patients,mean age（72. 1±11.5） years old,49% female（n=320） were recruited between January 2014 and December 2014.There were 211 patients（ 32. 3% ）with age above 80 years old, 135 patients （ 20. 7% ） had history of thromboembolism event, 410 patients （ 62. 9% ） had hypertension. Valvular, non-valvular and lone AF were 27. 6% ,42. 1, % and 30. 4%, respectively. Mean CHA2DS2-VASc score was 3.2, and 519 patients （79.6%） had a CHA2DSE-VASc score≥ 2. 257 patients （ 54. 4%） received either warfarin（n= 101,21.4%）or new oral anticoagulants（n= 156,33.0%）. Conclusions The AF patients in Macao are older,the percentage of valvular AF is higher.Due to more than half of the patients accepted anticoagulation therapy, the percentage of stroke is low.