精准医学和循证医学与精准外科的发展对肝细胞癌综合治疗模式的影响

Impact of precision medicine, evidence-based medicine and precision surgery on the multimodality therapy for hepatocellular carcinoma

精准医学的蓬勃发展推动了各类疾病诊断与治疗的进步，也对肝细胞癌的循证医学指南和综合治疗模式带来了冲击和变革。遵循精准医学大局观，以循证医学为基础，将肝细胞癌精准外科具体化，建立以精准肝切除术为核心，强调系统化并兼顾个体化的肝细胞癌综合治疗体系，最终实现患者总体获益，是“精准时代”赋予医者的新使命。

Precision medicine significantly promotes the diagnosis and treatment of various diseases, which also induces the revolution of evidence-based clinical practice guidelines, as well as multimodality therapy for hepatoeellular carcinoma （HCC）. In the application of the concept of precision medicine and evidence-based medicine, surgeons will concretize the precise surgery, establish an improved multimodality therapy for HCC, and ultimately achieve the goal of overall benefit. This is also a new task of surgeons in the precision medicine era.