摘要
目的:观察丹栀逍遥散治疗广泛焦虑性睡眠障碍的临床疗效。方法:将100例符合临床诊断的患者,随机分为治疗组52例及对照组48例。对照组予米氮平治疗,治疗组予丹栀逍遥散治疗。8周为1个疗程,在第2、4、8周进行随访,采用汉密尔顿焦虑量表(HAMA)评定治疗效果,使用匹兹堡睡眠质量指数(PSQI)评定睡眠质量。结果:治疗组效率为86.0%,高于对照组的68.9%,两组之间比较差异具有统计学意义(P<0.05);两组患者在第4周时HAMA评分都较治疗前下降,差异有统计学意义(P<0.05);在第2周时,治疗组PSQI评分较治疗前有所下降,差异有统计学意义(P<0.05);两组在第4周时PSQI评分较治疗前下降,差异有统计学意义(P<0.05)。结论:丹栀逍遥散能显著改善广泛焦虑性睡眠障碍患者的焦虑症状和睡眠质量,疗效确切,不良反应少。
Objective To observe the Dan Zhi xiaoyao powder in treatment of extensive anxiety the clinical curative effect of sleep disorders. Methods 100 cases in clinical diagnosis of the patients, divided into treatment group 52 cases and control group 48 cases. The treatment group to Dan Zhi xiaoyao powder treatment, control group with mirtazapine treatment. Eight weeks for a period of treatment, in 2, 4, 8 weeks follow - up, with Hamilton anxiety scale (HAMA) to evaluate the therapeutic effect, using the Pittsburgh sleep quality index (PSQI) to evaluate the sleep quality. Results The efficiency of the treatment group was 86. 0%, 68.9% higher than that of control group, comparing differences between two groups have statistical significance (P 〈 0. 05) ; In week 4 2 groups of patients when HAMA scores was decreased, the difference was statistically significant (P 〈 0. 05 ) ; in the second week, the treatment group of PSQI score was declined, the difference was statistically significant (P 〈 0. 05) ; The control group at 4 weeks PSQI score was decreased, the difference was statistically significant (P 〈 0. 05). Conclusion Dan Zhi xiaoyao powder can significantly improve extensive anxiety symptoms of anxiety in patients with sleep disorder and sleep quality, curative effect, less adverse reaction.
出处
《中国民族民间医药》
2017年第3期101-103,共3页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
丹栀逍遥散
广泛焦虑性睡眠障碍
临床观察
Dan Zhi at large
Extensive Anxiety In Sleep Disorders
Clinical Observation