期刊文献+

循环肿瘤细胞在乳腺癌诊疗中的应用 被引量:4

The application of circulating tumor cells in the diagnosis and treatment of breast cancer
原文传递
导出
摘要 近年来外周血循环肿瘤细胞(CTC)检测的临床应用无疑是精准医学领域的研究热点之一。CTC检测因其具有非侵入性、易获取、可反复采集、具有高度可重复性等优势,可对肿瘤治疗进行实时全面监测,在乳腺癌的复发预警、疗效及时评价、预后判断以及个体化治疗用药指导等方面均有大量的应用。 In recent years,the clinical utility of circulating tumor cells (CTCs)analysis from peripheral blood has undoubtedly become a popular topic in the field of precision medicine.CTCs analysis is a noninvasive,easily obtained and highly repeatable testing approach,and could be carried out in a real-time manner,which has never failed to surprise us with great progression in the detection of early disease,assessing prognosis,treatment response monitoring and individualized therapeutic direction in breast cancer.
作者 管秀雯 马飞 Guan Xiu- wen Ma Fei(Department of Medical Oncology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China)
出处 《国际肿瘤学杂志》 CAS 2017年第1期45-48,共4页 Journal of International Oncology
基金 国家自然科学基金(81472453)
关键词 乳腺肿瘤 血液循环 肿瘤标记 生物学 Breast neoplasms Blood circulation Tumor markers,biological
  • 相关文献

参考文献1

二级参考文献35

  • 1ASWORTH T R. A case of cancer in which cells similar to those in tumors were seen in the blood after death [J]. Aust Med J, 1869, 14: 146- 149.
  • 2LIU M C, SHIELDS P G, WARREN R D, et al. Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer [J]. J Clin Oncol, 2009, 27(31): 5153-5159.
  • 3JEMAL A, BRAY F, CENTER M M, et al. Glohal cancer statistics [J]. CA Cancer J Clin, 201 1, 61 (2): 69-90.
  • 4GANGOPADHYAY S, NANDY A, HOR P, et al. Breast cancer stem cells: a novel therapeutic target [J]. Clin Breast Cancer, 2013, 13(1): 7- 15.
  • 5WICHA M S, HAYES D F. Circulating tumor cells: not all detected cells are bad and not all had cells are detected [J]. J Clin Oncol, 20ll, 29(12): 1508-1511.
  • 6MOSTERT B, SLEIJFER S, FOEKENS J A, et al. Circulating tumor cells (CTCs): detection methods and their clinical relevance in breast cancer [J]. Cancer Treat Rev, 2009, 35(5): 463-474.
  • 7LAMBRECHTS A C, BOSMA A J, KLAVER S G, et al. Comparison of immunocytochemistry, reverse transcriptase polymerase chain reaction, and nucleic acid sequence-hased amplification for the detection of circulating breast cancer cells [J]. Breast Cancer Res Treat, 1999,56(3): 219-231.
  • 8SMITH B M, SLADE M J, ENGLISH J, et al. Response of circulating tumor cells to systemic therapy in patients with metastatic breast cancer: comparison of quantitati ve polymerase chain reaction and immunocytochemical techniques [J]. J Clin Oncol, 2000,18(7): 1432-1439.
  • 9CRISTOFANILLI M, HAYES D F, BUDD G T, et al. Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer [J]. J Clin Oncol, 2005, 23(7): 1420-1430.
  • 10HAYES D F, CRISTOFANILLI M, BUDD G T, et al. Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival [J]. Clin Cancer Res, 2006, 12(14 Pt I): 4218-4224.

共引文献20

同被引文献44

引证文献4

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部