摘要
目的调查住院2型糖尿病患者入院前降糖药物用药依从性状况,探讨其与血糖控制的关系。方法选取2型糖尿病住院患者415例,采用MMAS-8(■2006 Donald E.Morisky)对用药依从性进行评估,以糖化血红蛋白(Hb A1c)为血糖控制指标,分析其与用药依从性的相关性。结果用药依从性平均得分为(6.18±1.99)分,34.0%处于高等水平,性别、年龄、是否合并慢性并发症是用药依从性的影响因素,相关性分析显示用药依从性与Hb A1c之间呈负相关性(P=0.014)。结论本组糖尿病患者用药依从性水平欠佳,血糖控制不够理想,用药依从性水平是Hb A1c的影响因素,可以作为识别Hb A1c控制情况的工具。
OBJECTIVE To measure medication adherence to hypoglycemic drugs before admitted to hospital, assess the rela- tionship between medication adherence and glycosylated hemoglobin （HbAlc） among inpatients with type 2 diabetes. METHODS The medication adherence of 415 cases of type 2 diabetes inpatients were investigated through MMAS-8 （C 2006 Donald E. Morisky）, the association between medication adherence and HbAlc was analyzed. RESULTS The mean medication adherence score was 6. 18 ±1.99, 34. 0% which was found to be good adherent. Medication adherence to hypoglycemic drugs were influenced by sex, age and chronic complications, which was also found to be correlated to HbAlc negatively （P = 0. 014）. CONCLUSION Our results indicat that medication adherence to hypoglycemic treatment in our study is not optimal, the control condition of HbAlc is unsatisfacto- ry. Medication adherence to hypoglycemic treatment is related with HbAlc, therefore, medication adherence could be a tool help to identify patients with poor blood glucose control.
作者
吴萍
刘乃丰
WU Ping LIU Nai-feng(Department of Clinical Pharmacy, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanfing 210009, China Department of Cardiology, Zhongda Hospital, Southeast University, Nanfing 210009, China)
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第3期240-243,共4页
Chinese Pharmaceutical Journal
关键词
糖尿病
用药依从性
糖化血红蛋白
diabetes
medication adherence
glycosylated hemoglobin
