磁共振弥散加权成像（DWI）在食管癌放疗中的应用进展

Application of diffusion-weighted magnetic resonance imaging in radiotherapy for esophageal carcinoma

DWI作为MR功能成像的重要组成部分，可以提供定性和定量的信息以帮助肿瘤评估，更好的区分食管病灶及纵隔淋巴结转移。DWI—CT融合图像更有利于靶区勾画。在食管癌的放疗或同步放化疗中，监测ADC值变化有助于早期疗效预测和预后判断，DWI检查能弥补单纯依据造影评价食管癌近期疗效的不足。本文综述了DWI在食管癌诊断、靶区勾画、疗效评估及判断预后等在放疗中的应用进展。

As an important component of functional magnetic resonance imaging, diffusion-weighted magnetic resonance imaging （DWI） can provide qualitative and quantitative information for tumor evaluation and distinguish esophageal lesions and mediastinal lymph node metastasis. DWI-computed tomography fusion images facilitate the delineation of target volume. During radiotherapy or concurrent chemoradiotherapy for esophageal carcinoma, monitoring the changes in apparent diffusion coefficient value helps to predict the early treatment outcomes and proguosis;DWI compensates for the shortcomings of radiography alone in the evaluation of short-term treatment outcomes. This paper reviews the application of DWI in the diagnosis, delineation of target volume, assessment of treatment outcomes, and prognostic prediction in radiotherapy for esophageal carcinoma.